Zoning in Houston, what;s that? Houston has no zoning or setbacks - unless it's an SOB, Liquor Store or Cell Tower over 59ft you can pretty much build whatever you want. Look at the State TABC regulations and check with the City regarding your on premise and setbacks from Churches and Schools. The best bet is to build in the County or neighboring counties. No C.O.O. or other permits required with the exception of the County license. Most of the Houston area distilleries are located outside the City with the exception of three to my knowledge, Grateful Dane, Yellow Rose and Buffalo Bayou Distillers. - Whitmeyers, Raelin, Still Creek, BJ Hookers and Dash will be on the outskirts. Unless you want to spend a bunch of cash locate on the outskirts.