Sonja,
One of my clients is a rum distiller and we will be looking to implement in a similar fashion later this year.
There are two things to consider with using classes in QB Manufacturing edition. The first is the volume of transactions which you've already considered. The QB POS investment you can always make later when the tasting room deserves part to full-time staffing. The second thing to consider with classes is that you can only define them one way. For example you can use them for profit center reporting such as distillery and tasting, or you could use them for cost center reporting such as distillation, bottling, warehouse, etc. You get into trouble if you need both.
But if you stick with profit centers the setup is straight forward by enabling classes in preferences, setting up sales tax items (I believe lake county is 7% for merchandise such as t-shirts etc but would double check) and then entering the inventory items and pricing. You should think through the customer setup with the simplest option being a generic "tasting room customer." You also need to think how you can maintain an audit trail for credit card transactions if you go the generic route.
If you do decide to add your retail customers to quickbooks it does add time for the initial entry during checkout and you should make sure to select the customer type on their customer record to differentiate the retail vs. the wholesale customers.
The good news is that once you have your items (inventory / sales tax) and customers setup you can reuse them in QB POS if you decide to upgrade.
Hope this is helpful,
Rich