I was trying to set up a distillery in the garage, which is 24' from the house. I sent a diagram to my contact with TTB to check it was OK before progressing any further. He sent it on the the National Revenue Center and I got back a response saying the distillery must be at least 50' from a residence. I'm not sure what CFR this falls under or how the NRC fits into the regulatory scheme, but we put up a new building 120' from the house. The house is on the same property parcel, no problem there. The only headache was seperating with the insurance policies what is covered under the farm/home owner policy and what is covered under the distillery policy.